The Mumbai police on Wednesday arrested Republic TV editor Arnab Goswami from his residence in Maharashtra on charges of abetment in a suicide case.

The Republic TV editor claimed the police assaulted him while taking him away from his home early in the morning. He also alleged that the police manhandled his elder parents.

Architect and a famous interior designer, Anvay Naik had committed suicide on May 5, 2018, in Alibaug at Raigad district of Maharashtra, naming Goswami in the suicide note. His suicide note claimed that he had been forced to take the extreme step because of the financial burdens caused by the non-payment of dues amounting to over Rs 5 crore by Goswami and two others.

Naik’s wife Akshita had filed an FIR against Goswami two years ago. She had alleged that her architect husband had worked on an interior designing project, which was his last, for Republic TV office and Goswami had refused to pay him the dues.

Naik and his mother Kumud had committed suicide two years ago, under financial distress, his wife had alleged.

In May 2020, Maharashtra home minister Anil Deshmukh had announced a fresh CID investigation into the case after Adnya Naik, daughter of Anvay Naik, approached him and complained that the Alibaug police had not investigated the ‘non-payment of dues from Arnab Goswami’s Republic TV, Hindustan Times had reported. Any kind of assistance for overcoming suicidal thoughts is available on the State’s health helpline 104 and Sneha’s suicide prevention helpline 044-24640050

Pujya Shri Moraribapu will start “851st Ram Katha” at Lord Krishna’s childhood place Shri Ramnarethi Dham from 19th November. Shri Morari Bapu will recite the Ram Katha for 11 days in the presence of Pujya Swami Karshani Gurusharananandji Maharaj. Considering the Covid guidelines issued by Uttar Pradesh government only limited number of followers will be allowed at the venue.

Those who won’t be able to join the Katha can watch the live telecast of Ram Katha from November 19, evening 4:00 pm to 7:00 pm and 20 to 29 November in the morning from 9:30 am to 1:00 pm on Aastha Channel. Pujya Shri Moraribapu will recite the “851st Ram Katha” at Sri Ramanarethi Dham, Mahavan (Gokul), Mathura.

Lockdown has had a huge impact on all our lives, but digital marketer Arvin Subramanian has used it to his advantage to become a best-selling author with his book – Get Vocal for Local!

Through his book, “Get VOCAL for LOCAL”, Arvin offers solutions pertaining to digital marketing and content development to brands, marketers as per the need of the hour – Getting Local!

Digital Marketer Arvin Subramanian released his first book “Get VOCAL for LOCAL”, this Wednesday. The book revolves around how brands should localize their digital content to reach regional audience. The book analyses online consumption patterns of regional users and offers corresponding strategies to win them over. The solutions provided in the book come in handy for brands who look to go local!

Speaking about his journey of writing the book, Arvin says, “With Lockdown, there was a dull phase. Not much was happening and it became frustrating over a point of time. That’s when I started to focus on building my personal brand. Writing a Book is usually a long, time consuming process. But the lockdown situation, helped me focus and Fastrack that process”.

Arvin didn’t stop with just releasing his book, but also made it the Number 1 Best Seller, by marketing it effectively. However, it comes as no surprise, as the book itself is about digital marketing strategies. About the efforts to make his book, ‘the Best Seller’ – Arvin says, “The secret lies in the research. The Book deals with a very niche subject. The selection of the subject went like this: Marketing – Digital Marketing – Regional Digital Marketing – Regional Digital Content Marketing. This is an unexplored territory. Thus, the positioning of the book, played a huge role in winning over the audience.”

Apart from the positioning, Arvin also came up with multiple video teasers about the chapters and also indulged in influencer marketing. About his marketing strategy, Arvin says, “The idea was to cater directly to the target audience. I had taken guest lectures, pre-release seminars and fire side chat sessions to media management students. The video bytes from such sessions helped me to put various teasers about the chapters”. He has also put out the first two chapters as ‘Free to read’ for potential buyers, to have a sneak peak of the book.

About the theme of the book – Arvin considers getting local is a critical step in today’s scenario. With new users from regional, rural markets joining internet on a daily basis, it is important that a brand communicates to them in a relevant manner. Through his book, Get VOCAL for LOCAL, he offers practical solutions pertaining to digital marketing and content development to brands as per this need of the hour.

He concludes “Earlier brands could work out a central strategy, that could be implemented across all regions. But with today’s internet scenario, it is necessary that it communicates in the language and the style that would suit the regional audience. Only then brand communications can be successful”.

Researchers have traced a mechanism by which insulin overload in the body causes insulin resistance that is associated with diabetes. They have found the drug that is used in treating opioid addiction can potentially reverse this phenomenon.

The results of the research work by Indian Institute of Technology at Mandi that was funded by the Science & Engineering Research Board (SERB) grant, have recently been published in the Journal of Biological Chemistry. The paper has been authored by the lead scientist of this research Dr. Prosenjit Mondal, Associate Professor, School of Basic Sciences, IIT, Mandi and Co-investigators on the study were research scholars, Abhinav Choubey, Khyati Girdhar along with Dr. Debabrata Ghosh,  Aditya K. Kar, and  Shaivya Kushwaha of CSIR-IITR, Lucknow and Dr. Manoj Kumar Yadav of SRM University, Delhi-NCR, Sonipat, Haryana,

Insulin, a hormone produced by the pancreas, is used by cells to absorb glucose from the blood. Type-2 diabetes results when cells lose their ability to use insulin due to a variety of reasons. Insulin resistance is intricately linked to a condition called hyperinsulinemia, in which there is excess insulin traversing the bloodstream. The relationship between insulin resistance and hyperinsulinemia is cyclic – each increases the occurrence of the other. While it is obvious how insulin resistance leads to hyperinsulinemia – when cells cannot use the insulin, it just remains in the blood – the converse of how hyperinsulinemia increases insulin resistance has hitherto remained unclear.

“We have known that one of the causes of insulin resistance is inflammation”, says Dr. Mondal, “We wanted to find out if and how hyperinsulinemia invokes inflammation in the body, which would provide the link between the two conditions”.

The researchers identified a critical protein molecule – SIRT1 which is repressed in hyperinsulinemia.  They discovered that a decrease in SIRT1 activates another protein called NFkB, which instigates inflammation, thus providing the link between hyperinsulinemia and systemic inflammation.

The team has also discovered a solution to this problem. The researchers found that low-dose naltrexone (LDN), a drug commonly administered for opiate addiction, can activate SIRT1, thereby, reducing inflammation and increasing insulin sensitivity of cells.

The significance of this discovery is enormous. “Naltrexone at low doses could potentially restore some of the diabetes-associated events in cellular and animal models”, says Dr. Mondal, who is confident that this is a viable path to follow for Type-2 diabetes management. Naltrexone is already an FDA-approved drug that is used for the treatment of opioid addiction and can easily be repurposed for inflammation reduction and diabetes control. The research team intends to study this thread further, to understand the mechanistic aspects of LDN’s effects on hyperinsulinemia-induced inflammation and resulting insulin resistance.

The study by the IIT Mandi researchers and its collaborators is timely given the urgent need to understand and address the issue of diabetes in India. “India is the diabetes capital of the world”, says, Dr. Mondal , adding that one of every six diabetics in the world is Indian.  “It is important to understand the various causative factors for diabetes to find cures and management strategies”, says the lead researcher, whose work seeks to understand and treat insulin resistance.

A new global assessment of purchasing agreements for COVID-19 vaccines reveals that high-income countries, as well as a few middle-income countries have already purchased nearly 3.8 billion doses, with options for another five billion. The analysis, released by the Duke Global Health Innovation Center, shows that many of these countries will be able to vaccinate their entire populations—and some many times over—before billions of people are vaccinated in low-income countries.

While other assessments have warned of potential inequalities in vaccine access, this new analysis is the first to quantify the amount of vaccine doses that are being claimed by country-level agreements and how this could delay access to COVID-19 protection across large regions—including sub-Saharan Africa—until almost the middle of the decade.

“An ambitious effort to create a global system of vaccine equity is being undermined as a handful of countries—including those who made a commitment to equality—secure as many doses as they possibly can,” said Elina Urli Hodges, MSPH, who leads the Center’s Launch and Scale Speedometer, an initiative that identifies impediments to delivering health innovations to low-income countries. “Countries are hedging bets by making direct deals while also participating in multilateral platforms, which drives inequality and threatens to prolong a global pandemic.”

The Launch and Scale analysis revealed that while it will likely take three to four years to manufacture enough vaccines to cover the world’s population, nearly four billion doses of COVID-19 vaccine candidates are already part of bilateral advance purchasing deals involving mainly high-income countries, vaccine developers and global vaccine manufacturers. Another five billion doses are the subject of negotiations among these same parties that have yet to be finalized. Meanwhile, the study found that only enough doses to cover 250 million people have been confirmed as purchased thus far by COVAX, a global effort involving both wealthy and poor countries that has promised equal access to COVID-19 vaccines globally, regardless of income levels.

In fact, the data reveal that several COVAX signatories, including the United Kingdom (UK), the European Union (EU) and Canada, are effectively undermining the pact by negotiating “side deals” for large vaccine shipments that will “result in a smaller piece of the pie available for equitable global allocation.”  Yet the analysis shows that not a single low-income country has made a direct agreement to purchase vaccines, suggesting that low-income countries will be limited to the COVAX pact to secure vaccines. 

  Finite global manufacturing capacity

“There are negotiations underway in which vaccine-rich countries would allocate doses purchased through advance market commitments to the COVAX effort after they have vaccinated a certain portion of their populations,” said Andrea Taylor, MSW, who led the analysis for the Launch and Scale initiative. “But there’s no requirement, and arguably little incentive to do so.”

Taylor and her colleagues conducted their assessment by reviewing available evidence from public sources through October 8, 2020, combined with interviews with global and regional vaccine experts, as well as Ministry of Health officials in select countries. The analysis looked at advance market commitments (AMCs) for COVID-19 vaccines in order to better understand their overall volume and ultimate destination.

The insights that emerged show that COVAX members Canada and the UK have already pre-purchased more than enough vaccines to cover their entire populations. The EU has secured the rights to 400 million doses for member countries, with future agreements under discussion, potentially raising that number to almost two billion. The United States (US), which is not part of COVAX, already has agreements to purchase enough doses to cover 230% of its population and could eventually control 1.8 billion doses—about a quarter of the world’s near-term supply. None of the vaccine candidates yet have regulatory approval, however, so countries are hedging bets by purchasing multiple candidates and some portion of these doses may never materialize. The UK, for example, has made AMCs with five different vaccine candidates, using four different vaccine technologies.

Among middle-income countries, the Launch and Scale data show that Brazil and India—each of which have large vaccine manufacturing infrastructure—already have secured the rights to enough vaccines to cover about half of their populations and are negotiating additional deals. It also shows that some countries, such as Peru, are using their status as the site of COVID-19 vaccine trials to secure AMCs for vaccines—though Peru is also participating in COVAX to help cover its needs.

According to the analysis, the root problem is that finite global manufacturing capacity is colliding with wealth disparities and self-interest to create a zero-sum game where low-income countries simply can’t compete.

“High-income countries are making deals with major vaccine developers who are in turn reserving the lion’s share of the world’s manufacturing capacity to meet those commitments,” Taylor said. “We’re rapidly reaching the point where soon, even countries that have the finances to shop for vaccines will find there is no manufacturing capacity available to fill their needs. Even with new investments to build or retrofit additional facilities, there is a limit to how much global vaccine manufacturing capacity can expand in the next few years.”

For example, the study reveals that a pair of vaccine candidates—one from the Oxford University/Astra-Zeneca (AZ) vaccine partnership and another from the American vaccine developer Novavax—are the subject of agreements with global manufacturers to produce 3.73 billion doses. And about 3 billion of those doses would come from the Serum Vaccine Institute of India. Meanwhile, both vaccine candidates are the subject of large pre-purchasing commitments from high- or middle-income countries. The Oxford/AZ vaccine candidate leads the pack for AMCs at more than two billion doses, though that includes between 300 and 500 million doses for COVAX. In response to this climate, COVAX has moved quickly to reserve manufacturing capacity in Spain and Korea for more than a billion doses of one or more vaccines that have yet to be selected.

There are hundreds of ways to make money. Whatever your zest of entrepreneurial streak may be, there are some sure-fire techniques to make it in the online world.  Everyone thinks of business but very few people make it big in life with their passion and hard work like Viraj Datt did in his 20’s. This young entrepreneur who is just 21 and based in Chandigarh- buzzing high in his ‘Sneakers’ business due to his passion. He supplies sneakers to the famous Bollywood celebrities like Actor Parineeti Chopra, Rapper Raftaar, singer and daughter of Aditya Birla Chairman- Ananya Birla, Rapper Divine, musician and rapper Manj Musik, musician RitViz, rapper Kr$na and many more.

His immense passion for shoes made him establish his own business, he created a page on Instagram (vj_kicks) on which he showcase his all new collection of sneakers.

At a very young age Viraj Datt developed his interest in badminton and represented Haryana & Chandigarh. He brought laurels to the state and UT by winning state championships. Later, Datt took admission in Badminton Academy in Bangalore where his love for sneakers began.

After practicing badminton daily, he along with his friends used to visit a mall nearby the academy. There Viraj found a big sneakers store and as a fashion lover, the young lad frequently started turning up there. At one point of time, he came to know about all the articles displayed in the store.

Viraj Datt said that the sneakers were very costly in that store and the starting price was Rs 10k. “I was just 15 years old at that time and as a young lad that much amount was quite high for me. However, the store manager witnessed that this boy loves sneakers. He became my friend and kept sharing about the new arrivals with me when I was in Bangalore. I gained interest and knowledge about sneakers and that was enough for me to kick start my own sneakers business. Later, I moved abroad for the training where I decided to come up with something of my own. I started selling sneakers on my Instagram page ‘VJ Kicks’, among my known and friends from where I made the profit and purchased my favorite sneakers,” Viraj Datt said.

Viraj Datt, popularly known as VJ Kicks among celebrities is successfully running his sneakers business and planning big in the coming future by expanding his sneakers venture.

The Public Affairs Index-2020 has ranked Kerala as the best-governed state. The Public Affairs Centre, which released its report in Bengaluru, has found Uttar Pradesh declared at the bottom in the category of the large states. 

In the annual report released on Friday, the city-based not-for-profit-organisation said the states were ranked based on a composite index in the context of sustainable development. The organisation is headed by former Indian Space Research Organisation (ISRO) chairman K. Kasturirangan. 

In the large state category in terms of governance, four southern states Kerala, Tamil Nadu, Andhra Pradesh and Karnataka took the top four ranks. Uttar Pradesh, Odisha and Bihar marked the bottom of the ranking, scoring negative points in the category, getting -1.461, -1.201 and – 1.158 points respectively. 

In the small state category, Goa ranked first with 1.745 points, followed by Meghalaya (0.797) and Himachal Pradesh (0.725). Worst performers who scored negative points are Manipur (-0.363), Delhi (-0.289) and Uttarakhand (0.277), according to the PAC report. 

Chandigarh was found to be the best governed Union Territory in the category of UTs with 1.05 PAI points followed by Puducherry (0.50), while Andaman and Nicobar (-0.30) was the worst performer. 

According to PAC, the governance performance is analysed in the context of sustainable development defined by three pillars of equity, growth and sustainability. Speaking on the occasion, Kasturirangan said: “The evidence that PAI 2020 generates and the insights that it provides must compel us to reflect on the economic and social transition that is underway in India.”

People are becoming more health-conscious amidst the Covid-19 pandemic resulting in demand for organic foods which is driving the exponential growth of organic farming. Interestingly, educated Indians from various walks of life have turned to their home farming plots and purchasing farming plots to grow healthy food. They are ensuring that organic certifications and independent studies support their vision for healthy food.

States like Sikkim and Arunachal Pradesh have embraced this trend and have made organic farming mandatory leading to healthy communities. So we can observe a positive trend and a scaling of such farms in India in the coming years.

Organic food is now being hailed as one of the best choices for consumers and farmers. Organically grown food is now part of the go-green lifestyle. This happened as a result of awareness campaigns directed at the farmers by agriculture scientists and health and wellness professionals.

“The ongoing pandemic has further encouraged the need to adapt and transition to a healthier lifestyle by using organically grown products”, said Mr. Mark Garvin, CEO of Organic Solution Inc, a Nagpur-based company dedicated to helping organic farmers to source organic fertilizers agriculture. Mr.Garvin, a first-generation entrepreneur with vast experience in the field of international business and organic agriculture, has received many awards for his business acumen and service excellence.

He added that a long-neglected area of healthy soil for regeneration is also being focused on because of years of mineral depletion in soil due to the preference for chemical fertilizers. There is certainly a connection between healthy soils and high-yielding crops. An increase in a healthy yield will help farmers improve their profitability and support their families.  

Organic farming, needless to say, is extremely crucial in sustaining the environment, minimizing climate change, and access to clean water. Mr. Garvin also mentioned that preserving natural resources is a key objective and said he wanted to ensure Organic solution Inc. would continue to promote ecological farming, nutrient-rich produce, and eliminate the use of synthetic and chemical fertilizers and pesticides. Some of their products include:

Liquid humic fertilizer EDAGUM®S? is applied in plant production for increasing the productivity of various crops by 10-50% and more; increasing plant resistance to drought, bacterial and fungal diseases; plant stress coping after application of plant protection products; improving the quality of produced plant production; increasing water holding capacity of sandy soils (at an average on 30%); restoration soil fertility; and many other. 

Cropsil,  a silicon-based plant nutrient, is applied in plant production to strengthen plant cell walls and also to produce healthier plants with increased resistance to pesticides and insecticides. It also helps in increasing the yields and tolerance to high salinity. 

Crop Care Protect is an extremely effective organic non-toxic mite and pest control technology. Eco-Cert certified as an organic pesticide, Crop Care Protect is extremely effective on flying and non-flying pests and mites.

Moreover, to provide farmers with cost-effective farming solutions, one litre of their product can accommodate 2.5 acres of land which minimizes the cost of farming up to 500 Rs Acre.

 Organic Solutions Inc abides by the ideology of conserving natural resources, limiting the carbon footprint, growing and eating locally grown and prepared foods, and making the world a better place to live in. This commitment helps it deliver the best quality organic fertilizer that is safe and environment-friendly.

 With like-minded companies across the globe, Organic Solutions Inc. and its partners have successfully supplied organic fertilizers over 10,000,000 acres of farmland in various countries. eg. The Netherlands, USA, China, Russia, Canada, Spain, Sri Lanka, Argentina, and many others.

The company has partnered with a talented pool of international R&D personnel, who function intending to carry out detailed research works in new fertilizer formulations in the field of organic and biofertilizers. The team has so far developed world-class technologies in bioavailable Silicic Acid, Humic and Fulvic acid fertilizer to enhance organic agriculture inputs which are approved by various regulatory bodies in India, Russia, EU, France, USA, Canada, Jamaica, Chile, etc.

Midway Seeker revolves around manifesting oneself in understanding the spiritual, emotional and physical dimensions of the world by manoeuvring all aspects to seek the reason behind this cycle of life. Advait Ji found the midway seeker phenomenon to use yoga as a medium to attain awakening – both mental and physical nourishment.

‘A healthy mind resides in a healthy body’ -believing in this concept, Advait Ji endeavoured in providing yoga therapy which aims in integrating mind, body and spirit. In this era of technology and gadgets, we are so indulged in the materialistic things around us that we have lost sight of the spiritual things. By being a Midway Seeker, he is bringing in the alignment of the physical body with the soul which eventually helps us in taking steps towards our intellectual and emotional growth. Yoga considers the body as energy channels which if taken proper care of, would make us physically fit and would also help us to keep our mind stress-free and clear.

Yoga helps to replenish our body and soul and it also stimulates us to explore the aspect of knowledge that we have not traversed yet. When we dedicate ourselves to discovering the ultimate need for our existence, we open a plethora of opportunities that change the way we perceive everything around us. For this reason, Advait Ji uses Yoga to help people to recover from their problems and attain a balance between worldly things and divine needs.

He diagnoses physical ailments of people and combines Ayurveda, Panchkarma and therapeutic yoga to heal them. Modern science has identified this as Psychosomatic disorders and accepts that Yoga and Ayurveda is a solution to them. All he wishes for is to help people realise the importance of yoga so that they can widen their horizons of knowledge and thus, motivate them to achieve greater things in life.

Anusheel’s wish was to meet him once now for him this will always be a dream, he was deeply saddened by his passing away, who died at the age of 90 last Saturday. Anusheel became his fan through his Bond movies, beside a James Bond Star and Actor he was also a Kyokushin Karate Member and practitioner too, the same Karate style Anusheel practices, that made Anusheel more fond of him. He also listed some of his favourite Sean Connery movies, must watch according to him was Dr No, Goldfinger, Thunderball, From Russia with Love, Murder on the orient express, The Untouchables, Indiana Jones & the last crusade, The League of Extraordinary.

As we all know Anusheel is Indian National Kyokushin Karate Champion & Lifetime Member of the International Karate Organization Kyokushinkaikan led by Kancho Shokei Matsui, many of us in India know or not but Anusheel wished to let the Indian audiences & Kyokushin Karate practitioners in India especially know that Sosai Mas Oyama, the founder of Kyokushin Karate-The Strongest Karate, trained James Bond Star Sean Connery. Not only did Sosai Mas Oyama train Sean Connery, but he was also granted the rank of 1st Dan Black Belt (Honorary Shodan). Anyone familiar with the militaristic training requirements set by Sosai Oyama understands what a momentous accomplishment it was to train with Sosai Oyama at Honbu in Tokyo, Japan, so much so that even the Honorary title is impressive.

Few Don’t believe it Connery know and trained with Sosai Mas Oyama. He shared those pics which he gives credit to original content/post uploader on the Internet.

The gentleman next to Sean Connery receiving his Dan Certificate from Sosai Oyama is Donn Draeger trainer, accomplished Martial Artist and choreographer for the Bond Movies. Standing Sosai Oyama and James Bond how cool was that.

Anusheel extended his heartfelt gratitude “Rest in Peace Sir and Big Osu to you, your fan and admirer” to the true legend Sean Connery, who defined James Bond, he will always live through this movies and in the hearts of his millions of fans & every Kyokushin Karate practitioners around the world.